
This story reminds me of The Onion. US scientists say they have successfully reversed the effects of Alzheimer's with experimental drugs, but they can't remember where they wrote their conclusions!
But seriously, the drugs target and boost the function of a newly pinpointed gene involved in the brain's memory formation. In mice, the treatment helped restore long-term memory and improve learning for new tasks, Nature reports. The same drugs - HDAC inhibitors - are currently being tested to treat Huntington's disease and are on the market to treat some cancers.
They reshape the DNA scaffolding that supports and controls the expression of genes in the brain.
The Alzheimer's gene the drugs act upon, histone deacetylase 2 (HDAC2), regulates the expression of a plethora of genes implicated in plasticity - the brain's ability to change in response to experience - and memory formation.
Lead researcher Professor Li-Huei Tsai explained: "It brings about long-lasting changes in how other genes are expressed, which is probably necessary to increase numbers of synapses and restructure neural circuits, thereby enhancing memory.
HDAC inhibitor treatment for humans with Alzheimer's disease is still a decade or more away, researchers said.
Ten years.... hmmm. that fits in perfectly in my time table. So have a great day and now you don't have to worry too much about forgetting where you put your keys.
Custom Medical Stock Photo has a terrific file of images about Alzheimer's Disease.
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